Electrical and heat loads have complementary characteristics in the peak-valley distribution in combined heat and power systems. In optimal dispatch, these complementary characteristics can effectively enhance the peak load regulation and alleviate the wind power curtailment caused by the strong coupling in electricity and heat. Therefore, this paper studies the optimal dispatch of a combined heat and power system considering the coordination of heat load elasticity of heating buildings and the time-of-use electrical demand response. The synergistic promotion mechanism of wind power integration by electrical and heat loads is expounded. From the characteristics of heat and power loads, the heat elastic load model of heating building and the model of time-of-use demand response are established respectively. Then, the coordinated response model of the heat and power loads is established. Incorporating the multi-energy loads model, a day-ahead dispatch model of the combined heat and power system considering the coordination of loads is constructed. The analysis of the example shows that the coordination of heat load elasticity of heating building and time-of-use demand response can effectively improve the operational economy of the system and promote wind power accommodation. This work is supported by the National Key Research and Development Program of China (No. 2017YFB0902100).