The power cells can be damaged when short-circuit occurred in the three-phase four-wire 400 Hz solid-state power supply. The traditional methods can not ensure the rapid removal of short-circuit fault. In allusion to their limitation, a method of short-circuit protection based on software-hardware coordination control is presented. The method determines the conditions by using the current limit and the rate of transient short-circuit change. The method can overcome the instantaneous weak overload of power electronic devices and ensure the rapid removal of short-circuit fault and the continuous power supply by the quick turnoff of solid-state switch at the zero crossing and the constant-current source. The experiment results show that the method is useful and effective.