With the increasing frequency of typhoon disasters due to global climate change, the failure rates of power equipment have risen significantly, posing a serious threat to the safe and reliable operation of power grids. To enhance the resilience of power systems, a composite security-constrained unit commitment (SCUC) decision-making method when there are typhoon disasters is proposed, incorporating source-network-load collaborative optimization. First, based on historical typhoon data and the Rankine wind farm model, wind turbine output and line fault models are constructed. Then a set of uncertainty scenarios for fault decisions is created using the state sampling method. Next, separate decision models for SCUC, load shedding, and line restoration are developed for different response strategies. A robust optimization approach is employed to address the uncertainty of line faults, and is introduced as a virtual “typhoon disaster” agent in a multi-agent game framework, where each of the above decision models serves as an agent. Finally, an iterative search method is applied to solve the model. Simulation results demonstrate that the proposed approach can minimize load shedding while ensuring economic operation of the system, thereby improving the resilience of the power system during typhoon disasters.