There are emerging challenges posed by the integration of a large number of distributed generations (DGs) into power distribution networks. Thus this paper proposes a novel bounded area-protection that combines negative-sequence quantity sorting with 5G communication. To achieve a bounded protection range with flexible configuration and address the issue of main criterion failure in extreme conditions, it introduces a measurement-compensated voltage magnitude comparison criterion that eliminates the need for re-adjustment. For information exchange, a 5G communication method with timestamps is proposed, further reducing the synchronous communication requirements of the proposed protection scheme by leveraging the communication characteristics of distribution networks. Simulation results demonstrate the successful application of the proposed criteria to lines with unpredictable branches without relying on data synchronization communication. Compared to traditional three-section current protection, the new protection scheme significantly enhances fault clearance speed, ensuring that the fault’s maximum response time remains within 90 ms. Even under conditions involving tens of ohms of inter-phase arc transition resistance and ground resistance, the proposed scheme maintains excellent fault identification capability. In comparison to amplitude differential protection, the proposed protection exhibits stronger adaptability and operational stability against unpredictable branches.