With the advent of distributed generation, the desire for high boost DC-DC converter development has increased. In order to obtain a higher voltage gain, a hybrid high voltage gain non-isolated single switch DC-DC converter for photovoltaic power generation is proposed. The proposed converter connects the standard conventional Boost and Cuk converters in parallel. The circuit topology, working principle and circuit parameter design are discussed in detail. Simulation is carried out based on Matlab/Simulink and the 150 W experimental prototype based on MCU. The simulation and experimental results are in good agreement with the theoretical analysis.This verifies the correctness of the theoretical analysis and the effectiveness of the proposed hybrid DC-DC converter topology. The proposed hybrid topology uses a single switch with a lower component-count and provides a higher voltage gain than non-isolated traditional converters. This topology provides continuous current mode operation with the help of a single power switch, which gives less voltage stress on the controlled switch and diodes. This work is supported by the National Natural Science Foundation of China (No. 61702182) and Outstanding Youth Project of Hunan Education Department (No. 20B328).