The operational status monitoring and condition maintenance of relay protection is important for improving the reliability of relay protection operation. A real-time evaluation method of relay protection based on wide area information is proposed, and a real-time evaluation system is developed. The real-time evaluation system obtains information from the grid dispatching system, the master station of relay protection and the master station of the fault recorder to evaluate the operation of relay protection in real time and generate a corresponding report. The system greatly reduces the time of fault analysis and improves its quality. The system comprehensively analyzes the protection information of all the inactive lines adjacent to the fault line, analyzes their behavior from the recording information and intermediate node information of these devices, determines hidden dangers, and ensures the safe operation of the power grid. The system has been put into operation in the dispatching center of the State Grid Anhui Electric Power Company. The operational results show that the scheme has good feasibility and effectively improves the maintenance efficiency of operation and maintenance personnel. This work is supported by the Science and Technology Project of State Grid Corporation of China (No. 521200190081).