Intelligent substations are widely used, and have higher requirements for the secondary maintenance of substations. To improve the maintenance efficiency of the smart station, a one-click security measure application module integrated in the monitoring system of the station is proposed. The general rules for automatic generation of operation-order-sheet for an intelligent substation are designed. The one-click safety measure application module is deployed in the integrated monitoring system of an intelligent substation. The advanced functions such as automatic generation of operation-order-sheet, automatic sequence control execution and check of operation-order-sheet and recovery of the safety measure are realized. The safety measurement system proposed in this paper has been tested at the State Grid Hebei Electric Power Company Test Station. The test results show that the scheme has good feasibility and can effectively improve the maintenance efficiency of operation. This work is supported by the Transformation of Scientific and Technological Achievements Special Fund of Jiangsu Province (No. BA2016057) and the Science and Technology Project of Hebei Electric Power Company (No. KJ2019-018).