With the development of smart grids, a large number of high-permeability distributed power sources are connected to the grid in cluster form. The coupling between communication networks and power networks is deepening, and the architecture of Cyber-Physical System (CPS) is constantly improving. In this paper, a hierarchical collaborative control scheme based on multi-agent consistency for intra-group autonomy and inter-group coordination is proposed for high-ratio distributed power cluster regional power grid. In order to fully consider the impact of communication system on cluster control, this paper builds a real-time power information simulation platform based on RT-LAB and OPNET, which can accurately reflect the performance of communication network and the whole process of sending, communicating, delaying and responding to accurate simulation strategy. In addition, this paper implements the CPS hardware in the ring, the cluster controller hardware is developed for the proposed cluster control strategy. The simulation of the cluster example in different communication scenarios under the CPS architecture verifies the effectiveness of the cluster control strategy and the feasibility and accuracy of the simulation platform. This work is supported by National Key Research and Development Program of China (No. 2016YFB0900400) and National Natural Science Foundation of China (No. 51477029).