In order to solve the protection configuration problem of two-terminal flexible DC distribution network when the converters access to DC buses directly, this paper presents a new protection scheme based on single-end electrical signals. Firstly, the fault characteristics of the two-terminal flexible DC distribution network are analyzed, and the difference of discharge characteristics of converts’ shunt capacitor at different busbars are analyzed especially. A main protection is designed based on the differences, which can identify fault areas effectively and isolate the fault within 5 ms. In order to solve the issue of failure detection of main protection, the backup protection is designed based on overcurrent criterion and action delay. Finally, a PSCAD/EMTDC simulation model is built and the simulation results show that the schemes are effective. This work is supported by Natural Science Foundation of Xinjiang Uygur Autonomous Region (No. 2016D01C036).