The island microgrids containing diesel generators, photovoltaic cells and energy storage units provide an effective solution to the energy supply in remote areas. However, due to the double uncertainty of renewable energy output and island microgrid load, there is still a lack of effective energy control strategies to ensure the reliability and economy of power supply of isolated island microgrids. Based on uninterrupted power supply, how to realize the economic operation of multi-source island microgrids is a new problem that the grid company needs to solve urgently. In this paper, a multi-source island micro-network economic operation control strategy based on the Model Predictive Control (MPC) is proposed to minimize the cost operation and reduce the adverse influence of load and the fluctuation of PV power fluctuation. The effectiveness of the control strategy is verified by analyzing the economic operation cost of a village in northwest China. This work is supported by Science and Technology Project of State Grid Corporation of China (No. 52110417001G).