Problems of switch position location and fixed value setting are common in distribution network, which causes skip tripping or simultaneous tripping of line switches. In view of this situation, considering the influence of voltage level of substation in 10 kV distribution network on the time limit of protection and the inrush current of transformer substation, different switching hierarchical protection methods are put forward according to different substations, and different hierarchical protection principles and corresponding setting principles are given respectively. On this basis, a statistical investigation on 10 kV distribution line system impedance in a domain is made, corresponding grading switch setting position table and setting limits are given. Simulation results and practical application results show the effectiveness of the proposed method. This work is supported by Science and Technology Project of State Grid Jiangxi Electric Power Company Ltd. (No. 52182017001B) “Auxiliary Decision-making Approach and Platform Research and Application of Switch Selective Protection in Distribution Network Line”.