A centralized grid-connected photovoltaic (PV) station is a widely adopted method of neutral grounding using resistance. It requires that the fault can be quickly removed in the event of grounding faults. Therefore, the study of short circuit zero sequence current calculation of grid-connected PV station is of great significance. To this end, an engineering calculation method for zero-sequence current of grid-connected PV station with neutral grounding resistance is proposed. This method takes into account the requirement for grid control of the photovoltaic inverter Low-Voltage Ride Through (LVRT), at the same time, the value of each parameter in the formula can be easily determined by looking up the table, the solution of zero-sequence current is simple and direct. Through an actual PV station for calculation example, and the results verify the practicability and validity of this method. This work is supported by National Natural Science Foundation of China (No. 51577018).