In order to meet the distributed computing demands of the power system security stability analysis, the multi-layer asynchronous concurrent computing architecture for power system security stability analysis coarse granularity paralleling which is based on asynchronous concurrent and workflow technologies is proposed. Through with multi-scheme and multi-function asynchronous concurrent computing mechanism, multiple functions tasks of different periods data are unified dispatching management for improving the utilization of computing resources without modifying the algorithm of security and stability analysis program. In order to satisfy the custom requirements of calculation procedure in different scenarios, all functions are unified encapsulation based on the process definition method for the power system security stability analysis functions. The application in power system security and stability integrated and coordinated defense systems of provincial and above power grid demonstrate the validity of the method. This work is supported by Science and Technology Project of State Grid Corporation of China “Research on Online Risk Assessment and Decision-making Techniques for Power Network Load Reduction Measures”.