Pneumatic control valve is an important control device in industrial production, and its fault diagnosis technology is paid more and more attention. The simulation model of pneumatic valve is established based on the DAMADICS platform, and the fault data is generated by DABLib module. The principal component vector of fault data is extracted and the PLS model is constructed. The multidimensional high-dimensional space is mapped to the low-dimensional space, and its data is compressed and normalized. The results of Hotelling T² and SPE statistical analysis are used to analyze the residuals of the test data and the actual data generated by the platform. The simulation results show that the method realizes the diagnosis and classification of the valve faults, and the results are effective. This work is supported by Hunan Science and Technology Department Project (No. 2012FJ4251) and Hunan Provincial Department of Education Project (No. 20150637).