The fast development of smart grid ensures a bright future of intelligent substation. Intelligent substation differs much with the traditional substation in its structure, network communication method and the devices applied, which are all advantages of intelligent substation compared with traditional one. But in the practical operation, it also faces many problems in value sampling accuracy, clock synchronization and electromagnetic compatibility. The new concept “local protection” also brings some problems. The problems above are discussed and the current research results are listed, then the insufficient research points are pointed out and several suggestions and ideas for future research are proposed. This work is supported by Science and Technology Project of State Grid Corporation of China (No. 521999160004).