At present, the dispatching control system of power grid achieving safe and reliable remote sequence control to primary equipment, is one of the research topics of the development of smart grid in State Grid Corp of China. In this paper, the application of general service protocol in remote sequence operation is studied. From general service protocol for electric power system and master-slave station sequence control process, interactive service process, service interface and application implementation method of general service protocol in remote sequence control are researched. This method has been applied in practical engineering and has achieved good results.