This paper proposes a feasible power flow adjusting method for distribution network with distributed power sources. Based on the reactive power partitioned-balance areas of distribution network, load rate of partitioned areas is defined, and then an optimal adjusting method of reactive power balance considering substation coordination of automatic voltage system (AVC) is designed. This method includes an optimal adjusting method for the balance of partitioned reactive power compensation for distribution system and a substation AVC coordinated adjusting method. In the process, the first method is prior to the following method. For the former model, the immunity genetic algorithm (IGA) is employed, and for the other model, the direct solving method is used. The proposed method in this paper could obtain a feasible power flow solution with reactive power partitioned-balance, bus voltage magnitudes satisfying security constraints, and the lower real power loss, by means of using the adjusting strategy on reactive power compensation cabinets of distribution transformer on low voltage side and distributed power sources for both the balance of partitioned reactive power compensation for distribution system and coordinated control with substation’s AVC. Finally, a 10 kV 55-bus real system of Chengdu is simulated, verifying that the proposed method is effective. This work is supported by National Natural Science Foundation of China (No. 51577018).