Based on homogeneity, a new multi-object configuration method is proposed. To enhance the system reliability and homogeneity, a new multi-objective model is established. Then the relationship of reliability and feeder losses with different homogeneity is discussed, and an improved multi-objective harmony search algorithm is applied to the presented method. The test result by IEEE 33 bus system shows that the presented method is rational and effective, and the optimization solutions considering both system reliability and homogeneity are given so that the dispatchers can make choices according to the actual situation. This work is supported by National Basic Research Program of China (973 Program) (No. 2013CB228206), National Natural Science Foundation of China (No. 51177143), and Natural Science Foundation of Zhejiang Province (No. LZ12E07002).