To solve the issues of low calculating efficiency and long calculating time caused by large amount of anticipated multi-contingencies in the static security analysis of provincial power grid, an anticipated multi-contingencies automatic selection method based on fault influence domain is researched and implemented. Firstly transfer coefficient is used for signifying the active power flow change of devices before and after contingency of another device. Then according to the transfer coefficient, the devices which the power flow is significantly increased and closed to the short-term overload capacity are defined as the fault influence domain of certain device. Finally the important anticipated N-2 contingencies are automatically selected according to the relationship between every fault influence domain. The theory of this method is simple, and facilitates programming realization. The IEEE 39-bus system and actual provincial power grid examples prove the reliability and practicality of this scheme.