Due to the randomness and intermittent characteristics of renewable energy, a lot of renewable energy generation plugs into the microgrid and creates the imbalance between generation and load. Based on the advantages of huge potential capacity and fast power adjustment, this paper investigates frequency regulation of microgrid for application of a large number of light-emitting diode (LED) lamps. In order to acquire the signal accurately, a distributed signal acquisition approach is proposed based on unreliable communication with communication delay and noise. Signal measuring devices are performed only at distribution substations, and local communication between neighbors can facilitate consistent and accurate acquisition of signals for all LED lamps. Taking into consideration of the non-linear relationship between flux and power, a dynamic model of power adjusting with frequency is designed. Integrated with distributed acquisition approach, a multi-regional microgrid frequency control method is further proposed with consideration of LED lamps. Simulation results demonstrate that LED lamps participating in frequency significantly reduces the frequency fluctuation and increases the speed of recovery.