In order to ensure the distribution network reconfiguration more practical and effective, this paper presents a new reconfiguration method considering economy and power quality. Firstly, system performance indicators are raised including power loss and total voltage offset, then the normalization method is used to integrate two indicators and formation comprehensive performance indicators of distribution network, and finally by setting standard deviation for comprehensive performance indicators, the reconfiguration time is divided, by which the number of reconfiguration can be limited. Combined the characteristic of distribution network, the network structure is simplified, which reduces the optimization space of GA effectively; and the crossover ratio and mutation ratio that adaptively adjust are adopted during optimization, which improves the performance of the algorithm better. Simulation results on the IEEE-33 system indicate the correctness and effectiveness of the method.