Considerable studies have been discussed to compensate or minimize or eliminate the dead-time effect of three phase inverter. First, this paper analyzes the limitations of the previous strategies. Then, SVPWM sequence calculated by Immune Algorithm (IA) for dead-time elimination and compensation is proposed for the three-phase bridge inverter. The proposed scheme implements the dead-time elimination in most of the reference current fundamental period but switches to the novel dead-time compensation around the zero crossing point. Furthermore, the simulation results are given to verify that the THD of output waveform generated by SVPWM is significantly reduced and the amplitude of output voltage is improved.