To improve the efficiency of traditional relay protection setting value local modification, a setting value modified system based on EMS integration is presented. Based on the analysis of IEC104 expanding protocol, and on the basis of Yangzhou power dispatch automation OPEN-3000 system, the whole frame and software design of remote operation system are researched and proposed. To test the performance, the system is applied in Yangzhou 220 kV Guangling substation. The results show that the system can realize the setting value remote modification, the setting value zone remote switch and the soft plate control on-line, which improves the levels of dispatch management and operation management.