The control strategy of VSC-HVDC system is studied. A new control scheme and a controller are designed to solve the deficiencies of conventional PI control that it is hard to control under a large disturbance precisely. This paper adopts double loop control, in which the inner loop controller uses PI control and the outer loop controller combines the fuzzy control and artificial neural network, and uses genetic algorithm to optimize fuzzy neural network connection weights and membership function. Simulation results of drop of rectifier active power and three-phase short circuit show that this control method’s response speed and response accuracy are significantly better than that of the traditional PI control under a large disturbance.