TMS320VC5509A is a high-performance, 1ow-power, fixed-point TMS320C55x(tm) Digital Signal Processor with USB interface module. The chip of TMS320VC5509A and CPLD are used as the control and processing core of the multi-channel synchronous data collection and storage system. The USB module of the TMS320VC5509A is used to build up a data acquisition and USB data transfer system. It also introduces the software and hardware design of the system, analyzes the architecture of TMS320VC5509A USB module, and introduce a firm ware design based on TMS320VC5509A.